The Technology Inside Measura

The test library

The Measura test library

Every assessment in the suite, described twice — once for the person having it, once for the clinician ordering it.

Measura is a suite, not a single study, and the reason it works is that the individual assessments answer different questions. A normal ankle-brachial index does not rule out calcified arteries. A normal nerve conduction study does not rule out small-fiber damage. Reading them together is the point.

Circulation and the arteries

Ankle-brachial index

Blood pressure at the ankle compared with the arm, plus the toe-brachial index and an arterial stiffness index. Read more

Pulse volume recording

Limb volume change with each heartbeat — sensitive where a calcified artery makes the index misleading. Read more

Photoplethysmography

The shape of the pulse waveform at the finger and toe, measured with light. Read more

Arterial stiffness and endothelial function

How rigid the vessel wall has become and how well the lining responds. Read more

Laboratory panels

Insulin and glycemic markers, inflammatory markers, lipid particle analysis, thyroid and hormone panels. Read more

Nerves and the autonomic nervous system

Sudomotor testing

Sweat gland function measured by electrochemical skin conductance — a window on the smallest nerve fibers. Read more

Autonomic nervous system testing

Sympathetic and parasympathetic function at rest and under challenge. Read more

Heart rate variability

Beat-to-beat variation in time and frequency domains. Read more

Cardiac autonomic reflex tests

The standardized challenge maneuvers used to assess cardiac autonomic neuropathy. Read more

Metabolism, balance and cognition

Indirect calorimetry

Resting metabolic rate and respiratory quotient, measured rather than estimated. Read more

Bioimpedance body composition

Lean mass, fat mass and body water — the detail BMI throws away. Read more

Vestibular and balance testing

Inner-ear and oculomotor function, and objective fall risk. Read more

Cognitive assessment

A short structured screen that produces a comparable baseline. Read more

Talk to someone about testing

Tell us what you are trying to find out and we will explain which Measura assessments answer that question, what each one involves, and how the results are reviewed with a clinician.

4477 Woodson Rd, Suite 201, St. Louis, MO 63134. Monday to Friday, 9:00 a.m. to 5:00 p.m. Please do not send symptoms, diagnoses or images through a web form — a website form is not a secure medical channel. Call us with clinical detail.

Common questions

Do I have to have all of them?

No. The suite is selected to the question being asked, which is why the first step is a conversation rather than a booking. How a testing plan is chosen.

Are any of these invasive?

The in-office assessments use cuffs, surface electrodes and optical sensors. Nothing is injected and no radiation is used. What the appointment feels like.

Is this the same as a nerve conduction study?

No. Nerve conduction studies measure large myelinated fibers; sudomotor testing measures the small unmyelinated ones, which are often affected first. Small-fiber versus large-fiber neuropathy.

What happens to the results?

They are compiled into a single report and reviewed with a clinician. How to read your report.

Medically reviewed by Dr. Gurpreet Singh Padda, MD, MBA, MHP, medical director of Measura. Last reviewed .