Kindness Is the Baseline, Not the Achievement | The Pained Brain, Chapter 19

Comprehensive pain assessment

Comprehensive Pain Assessment: Measuring What the Short Visit Skips

A comprehensive pain assessment finds the pain generator by examination, then screens the terrain: A1c for glycemia, sleep apnea, and depression and anxiety. All are common in chronic pain, and all are easy to miss in a short visit graded on satisfaction.

Satisfaction scores reward the fulfilled request. The findings that change a chronic pain plan rarely surface in a visit organized around that score.

A chronic pain practice is graded on satisfaction, and satisfaction is earned by the fulfilled request. The workup that changes the plan, the prediabetic A1c, the untested apnea, the hip behind the back pain, earns nothing on that scale because the patient never sees it happen. The chapter video, Kindness Is the Baseline, Not the Achievement, presents chapter 19 of The Pained Brain by Dr. Gurpreet Singh Padda, MD, MBA, MHP, and Dr. KrisJay Fucanan, MD. Study-level detail and limits are in the book companion for chapter 19; the focus here is what a comprehensive pain assessment should measure and how to make that reproducible in primary care, pain, endocrinology and geriatric practice.

Do patient satisfaction scores get in the way of a full pain workup?

In 1,319 family medicine visits, denying a patient’s request cost satisfaction by request type: 19.75 percentile points for a referral, 10.72 for pain medication and 9.19 for a laboratory test. The last figure is the non-obvious one. A requested lab that is refused is penalized; a lab nobody thought to discuss is invisible. The score therefore punishes saying no and is blind to not looking. In a survey of 155 self-selected physicians in one state, 59 percent reported compensation tied to satisfaction ratings, with a 3.9 percent response rate that limits how far the finding travels. The structural driver is plain enough: the metric rewards the visible transaction, and terrain screening is not visible.

How often does a second look change the pain diagnosis?

Extrapolated from three US observational studies, about 5.08 percent of adults experience an outpatient diagnostic error each year. Among 286 primary care referrals to a tertiary center, selected for diagnostic uncertainty, the referral diagnosis matched the final diagnosis in 12 percent, was refined in 66 percent and was distinctly different in 21 percent. In a single surgeon’s consecutive series of 200 back pain patients, 17.5 percent had hip or sacroiliac pathology alongside the spine, 8 percent had it without spine pathology, and 10 percent remained undefined after the workup.

None of those generators is found by a measurement service. They are found by examination and, where indicated, a diagnostic injection. The terrain is a separate question, and it is where objective testing earns its place.

What does screening find in people with chronic pain?

Glycemia. Point-of-care A1c in 84 hand clinic patients with carpal tunnel syndrome, trigger finger, Dupuytren’s contracture or De Quervain’s disease found 58.3 percent in the prediabetic range and 4.8 percent in the diabetic range; 43.4 percent of those with abnormal values had no primary care provider. The conditions were chosen for their known diabetes association, so the yield transfers to that presentation rather than to all pain.

Sleep-disordered breathing. Among opioid-treated Canadian pain clinic patients who completed polysomnography, 58.8 percent had sleep apnea, and each one-unit rise in STOP-Bang raised the odds of moderate-to-severe disease by 70 percent. In 90 consecutive Danish patients with high-impact chronic pain, 51.1 percent had obstructive apnea and 31.1 percent moderate or severe disease; Berlin ran 78.6 percent sensitivity and 45.2 percent specificity, STOP-BANG 71.4 and 58.1, and pain, disability and sleepiness did not distinguish the patients with apnea.

Mood and autoimmunity. Pooled across 376 studies, clinically significant depressive and anxiety symptoms ran 39.3 and 40.2 percent, rising to 54.0 and 55.5 percent in fibromyalgia samples. Thyroid peroxidase antibody positivity carried an odds ratio of 3.41 in fibromyalgia across five small case-control studies.

Low-yield tests. After full adjustment in 349,221 UK adults, vitamin D status carried odds ratios of 1.01 or lower for regional musculoskeletal pain; only deficiency below 25.0 nmol/L held a signal for widespread pain, at 1.26. Celiac screening in 62 Brazilian fibromyalgia patients found no cases. A comprehensive pain assessment is not every test; it is the tests the presentation points to.

Who needs a comprehensive pain assessment?

  • Chronic musculoskeletal or tendon-region pain in a patient without a recent A1c, or whose last value sat in the prediabetic band.
  • Patients on long-term opioid therapy, who warrant formal sleep testing rather than reliance on a questionnaire.
  • Patients carrying a fibromyalgia label, where mood screening and the metabolic panel belong in the same encounter.
  • Candidates for neuromodulation, since depression predicted first-year spinal cord stimulator explant at 1.39 in claims data.
  • Pain that has absorbed repeated procedures without a documented diagnosis.

Practice-level criteria are summarized under selection criteria.

Where Measura fits and where it does not

Measura [Cardiometabolic and Autonomic Health Analysis] is a testing service that reports to the ordering physician; it does not diagnose disease on its own and it does not treat. Two measurements carry this pathway: laboratory panels, which put A1c and fasting insulin in the chart, and bioimpedance body composition, which shows whether weight is muscle or adipose tissue. In older patients with chronic pain, cognitive assessment fits the same encounter, with the cognitive assessment and fall prevention workflow holding the two records side by side. Polysomnography, validated depression instruments and diagnostic blocks sit outside the service and should be ordered in parallel.

Metabolic health is the exception, not the default. The metabolically healthy share of American adults was under 12.2 percent on NHANES 2009–2016 and fell under 7 percent on the stricter criteria applied after 2021. In our clinic, under 1 percent of chronic pain patients qualify; that is a practice-reported figure from our own population rather than a trial outcome, and individual results vary. Dr. Padda’s own confession is that for years he read a borderline A1c as reassurance. That is the error a standing order is designed to remove.

Standing orders, documentation and follow-up in numbers

A standing order that attaches metabolic labs and body composition to new chronic pain referrals removes the decision from a crowded visit. The same results support cardiometabolic and cognitive documentation in MIPS and quality reporting as quality documentation rather than as an indication in themselves.

Follow-up needs its own numbers. Across 116 randomized trials and 49,785 patients, feeding patient-reported outcomes back to clinicians improved communication at a standardized 0.36, diagnosis and notation at a risk ratio of 1.73, and disease control at 1.25, while pain itself moved 0.00. Measurement is how a practice learns whether a plan worked, not the plan. Agree on the target up front: IMMPACT counts 30 percent as moderate and 50 percent as substantial improvement, and 110 patients defining success named 56 percent. Outcome tracking is described under what changes for the patient. The related tendon referral pathway is in tendinopathy as a metabolic signal, and patients can read the patient version.

Frequently asked questions

What belongs in a comprehensive pain assessment beyond the pain score?

A generator-focused examination, a mood screen, a sleep history with a low threshold for polysomnography in opioid-treated patients, and a metabolic panel including A1c. Add function and a documented target for improvement. The yield is highest where the presentation points: tendon and entrapment syndromes toward glycemia, fibromyalgia toward mood and thyroid autoimmunity. The broader reasoning is set out in clinical rationale.

Should chronic pain patients on opioids be referred for a sleep study?

The data support a low threshold. In opioid-treated pain clinic patients who completed polysomnography, 58.8 percent had sleep apnea, and in a high-impact chronic pain cohort the Berlin and STOP-BANG questionnaires missed a substantial share. Polysomnography is outside the Measura service and is ordered separately. Specialty-specific pathways are outlined under specialty applications.

Which screening tests have low yield in chronic pain?

Two published negatives are useful. Vitamin D did not independently predict regional musculoskeletal pain after confounder adjustment in 349,221 UK adults, and celiac screening in 62 fibromyalgia patients found no cases. Ordering what the presentation points to, and documenting why other tests were not ordered, keeps the workup defensible. Reading results in context is covered in interpreting the report.

How do Measura results reach the chart?

Results return to the ordering physician, who interprets them and decides on management. They can be filed as structured data so that the metabolic and body composition baseline stays visible when later procedure, therapy and behavioral health notes arrive, and so repeat values can be compared over time. The mechanics are described in getting results into the record.

Can terrain screening be built into an annual wellness visit?

Yes, as documentation. Glycemic, body composition and cognitive results fit the structure an annual wellness visit already uses, and they give a chronic pain patient a measured baseline outside the pain visit. The visit does not become a pain evaluation; it becomes the place where the terrain is recorded. Workflow is outlined in annual wellness visit integration.

How common are depression and anxiety in chronic pain?

Common enough that a comprehensive assessment should screen for both. Pooled across 376 studies of adults with chronic pain, 39.3 percent had clinically significant depressive symptoms and 40.2 percent had anxiety symptoms. In fibromyalgia samples the figures rose to 54.0 and 55.5 percent. Depression also predicted first-year spinal cord stimulator removal in claims data, which matters before any neuromodulation decision.

How common is sleep apnea in people with chronic pain?

In 90 consecutive patients with high-impact chronic pain, 51.1 percent had obstructive sleep apnea and 31.1 percent had moderate or severe disease. Pain, disability and sleepiness did not set those patients apart, and the Berlin and STOP-BANG questionnaires missed a real share of cases. That is why opioid-treated patients warrant a formal sleep study rather than a questionnaire alone.

What does Measura test as part of a pain assessment?

Two measurements carry this pathway: laboratory panels that put A1c and fasting insulin in the chart, and bioimpedance body composition that shows whether weight is muscle or fat. In older patients, cognitive assessment fits the same visit. Sleep studies, depression instruments and diagnostic blocks sit outside the service and are ordered in parallel. Every result goes to the ordering physician.

Make the terrain part of every pain workup

Learn how the Measura protocol adds metabolic labs, body composition and cognitive assessment to chronic pain referrals, with results returned to the ordering physician.

4477 Woodson Rd, Suite 201, St. Louis, MO 63134. Monday to Friday, 9:00 a.m. to 5:00 p.m. Please do not send symptoms, diagnoses or images through a web form — a website form is not a secure medical channel. Send your name and number and we will call you back.

References

  • Jerant, A., Fenton, J. J., Kravitz, R. L., Tancredi, D. J., Magnan, E., Bertakis, K. D., & Franks, P. (2018). Association of Clinician Denial of Patient Requests With Patient Satisfaction. JAMA Internal Medicine, 178(1), 85–91. https://doi.org/10.1001/jamainternmed.2017.6611
  • Zgierska, A., Rabago, D., & Miller, M. M. (2014). Impact of patient satisfaction ratings on physicians and clinical care. Patient Preference and Adherence, 8, 437–446. https://doi.org/10.2147/PPA.S59077
  • Heiting, C., Wickes, C. B., Katakam, S., Herrera, C., Li, B., Intravia, J., Nolan, J. E., & Nellans, K. W. (2026). Occurrence of Undiagnosed Diabetes Mellitus With Musculoskeletal Disorders of the Upper Extremity: Prospective Screening With Point-of-Care Haemoglobin A1c Fingerstick Testing. Musculoskeletal Care, 24(3), e70256. https://doi.org/10.1002/msc.70256
  • Chung, F., Wong, J., Bellingham, G., Lebovic, G., Singh, M., Waseem, R., Peng, P., George, C. F. P., Furlan, A., Bhatia, A., Clarke, H., Juurlink, D. N., Mamdani, M. M., Horner, R., Orser, B. A., & Ryan, C. M. (2019). Predictive factors for sleep apnoea in patients on opioids for chronic pain. BMJ Open Respiratory Research, 6(1), e000523. https://doi.org/10.1136/bmjresp-2019-000523
  • Larsen, D. B., Bendix, L., Abeler, K., Petersen, K. K., Sprehn, M., Bruun, K. D., Blichfeldt-Eckhardt, M. R., & Vaegter, H. B. (2021). Obstructive sleep apnea is common in patients with high-impact chronic pain – an exploratory study from an interdisciplinary pain center. Scandinavian Journal of Pain, 22(1), 106–117. https://doi.org/10.1515/sjpain-2021-0112
  • Aaron, R. V., Ravyts, S. G., Carnahan, N. D., Bhattiprolu, K., Harte, N., McCaulley, C. C., Vitalicia, L., Rogers, A. B., Wegener, S. T., & Dudeney, J. (2025). Prevalence of Depression and Anxiety Among Adults With Chronic Pain: A Systematic Review and Meta-Analysis. JAMA Network Open, 8(3), e250268. https://doi.org/10.1001/jamanetworkopen.2025.0268
  • Xie, Y., Farrell, S. F., Armfield, N., & Sterling, M. (2024). Serum Vitamin D and Chronic Musculoskeletal Pain: A Cross-Sectional Study of 349,221 Adults in the UK. The Journal of Pain, 25(9), 104557. https://doi.org/10.1016/j.jpain.2024.104557
  • Sembrano, J. N., & Polly, D. W. (2009). How often is low back pain not coming from the back? Spine (Phila Pa 1976), 34(1), E27-E32. https://doi.org/10.1097/BRS.0b013e31818b8882
  • Gibbons, C., Porter, I., Gonçalves-Bradley, D. C., Stoilov, S., Ricci-Cabello, I., Tsangaris, E., Gangannagaripalli, J., Davey, A., Gibbons, E. J., Kotzeva, A., Evans, J., van der Wees, P. J., Kontopantelis, E., Greenhalgh, J., Bower, P., Alonso, J., & Valderas, J. M. (2021). Routine provision of feedback from patient-reported outcome measurements to healthcare providers and patients in clinical practice. Cochrane Database of Systematic Reviews, 10(10), CD011589. https://doi.org/10.1002/14651858.CD011589.pub2
  • Van Such, M., Lohr, R., Beckman, T., & Naessens, J. M. (2017). Extent of diagnostic agreement among medical referrals. Journal of Evaluation in Clinical Practice, 23(4), 870–874. https://doi.org/10.1111/jep.12747

Related reading

Medically reviewed by Dr. Gurpreet Singh Padda, MD, MBA, MHP, medical director of Measura. Last reviewed .

Filed under: